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Translating translation into patient benefit for atopic eczema

Lookup NU author(s): Professor Nick ReynoldsORCiD, Dr Akash Sinha, Martina Elias, Dr Simon Meggitt



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


This review considers, in the context of British Skin Foundation (BSF)-funded translational research into atopic eczema conducted in Newcastle, the complex interactions between clinical and non-clinical scientists in both academia and industry and how this may have impacted on clinical care. However, research in individual centres does not occur in isolation and clinically relevant outcomes from collaborative research are increasingly supported through regional and national networks. This is illustrated by our trial of azathioprine in adults with atopic eczema conducted across centres in the North East of England that employed pharmacogenetic dosimetry. Correspondingly the formation of a UK Translational Network for Translational Research in Dermatology (UK TREND) has facilitated the development of a UK-wide network to support atopic eczema projects based on an e-Delphi prioritisation exercise.

Publication metadata

Author(s): Reynolds NJ, Sinha A, Elias MS, Meggitt SJ

Publication type: Article

Publication status: Published

Journal: British Journal of Dermatology

Year: 2016

Volume: 175

Issue: Suppl. S2

Pages: 8-12

Print publication date: 01/10/2016

Online publication date: 26/09/2016

Acceptance date: 25/07/2016

Date deposited: 14/06/2017

ISSN (print): 0007-0963

ISSN (electronic): 1365-2133

Publisher: Wiley-Blackwell Publishing Ltd.


DOI: 10.1111/bjd.14909

Notes: Special Issue: British Skin Foundation, Skin Deep - 20 Years of Research, 20th Anniversary Conference, 13th October 2016, Royal College of Physicians, London, U.K.


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