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Arguing against the proposed definition changes of PD

Lookup NU author(s): Professor Ian McKeith

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

As members of the Lewy Body Dementia Association Scientific Advisory Council, we aim to address some of the issues raised in the article titled Time to Redefine PD? Introductory Statement of the MDS Task Force on the Definition of Parkinson's Disease. In particular, we suggest that the 1-year rule distinguishing Parkinson's disease dementia from dementia with Lewy bodies is worth maintaining because it serves an important purpose in clinical practice and clinical and basic science research and when helping the lay community understand the complexity of these different clinical phenotypes. Furthermore, we believe that adding an additional diagnostic label, PD (dementia with Lewy bodies subtype), will confuse rather than clarify the distinction between dementia with Lewy bodies and PD or PD dementia, and will not improve management or expedite therapeutic development. We present arguments supporting our contentions. (c) 2016 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.


Publication metadata

Author(s): Boeve BF, Dickson DW, Duda JE, Ferman TJ, Galasko DR, Galvin JE, Goldman JG, Growdon JH, Hurtig HI, Kaufer DI, Kantarci K, Leverenz JB, Lippa CF, Lopez OL, McKeith IG, Singleton AB, Taylor A, Tsuang D, Weintraub D, Zabetian CP

Publication type: Article

Publication status: Published

Journal: Movement Disorders

Year: 2016

Volume: 31

Issue: 11

Pages: 1619-1622

Print publication date: 01/11/2016

Online publication date: 05/08/2016

Acceptance date: 03/06/2016

Date deposited: 15/12/2016

ISSN (print): 0885-3185

ISSN (electronic): 1531-8257

Publisher: John Wiley & Sons, Inc.

URL: http://dx.doi.org/10.1002/mds.26721

DOI: 10.1002/mds.26721


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Funding

Funder referenceFunder name
P50 AG005136NIA NIH HHS
P50 AG005131NIA NIH HHS
Z01 AG000932-01Intramural NIH HHS

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