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HLA-DRB1*15 and pediatric aplastic anemia

Lookup NU author(s): Dr Tevfik Dorak


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We report a positive association between HLA-DRB1*15 (p= 0.0002) in Turkish patients with pediatric severe aplastic anemia (SAA) and a paradoxically favorable influence of the susceptibility marker on the clinical response to immunosuppressive therapy. These findings point to an immune mechanism mediated by DRB1*15 in SAA which confers responsiveness to treatment.

Publication metadata

Author(s): Dorak MT; Oguz FS; Yalman N; Diler AS; Oguz R; Anak S

Publication type: Letter

Publication status: Published

Journal: Haematologica

Year: 2002

Volume: 87

Issue: 7

Pages: 772-774

ISSN (electronic): 0390-6078


PubMed id: 12091130