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Connecting chromosome replication with cell growth in bacteria

Lookup NU author(s): Professor Heath MurrayORCiD

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).

Abstract

For bacteria to proliferate they must duplicate their genetic material so that it can be passed to their progeny. This requires that DNA replication is coordinated with cell growth and division. In the natural environment bacterial growth is dynamic and strongly influenced by changes in nutrient availability. Recent studies have found that bacteria utilize a range of regulatory systems, many of them species-specific, to coordinate DNA replication with cell growth. This variability likely reflects the diverse lifestyles of different bacterial types.

Publication metadata

Author(s): Murray H

Publication type: Review

Publication status: Published

Journal: Current Opinion in Microbiology

Year: 2016

Volume: 34

Pages: 13-17

Print publication date: 01/12/2016

Online publication date: 25/07/2016

Acceptance date: 01/01/1900

ISSN (print): 1369-5274

ISSN (electronic): 1879-0364

Publisher: CURRENT BIOLOGY LTD

URL: http://dx.doi.org/10.1016/j.mib.2016.07.013

DOI: 10.1016/j.mib.2016.07.013

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