Browse by author
Lookup NU author(s): Dr Shaheda Ahmed, Professor Anne Dickinson
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
The workshop on "New Approaches to Investigate Drug-Induced Hypersensitivity" was held on June 5, 2014 at the Foresight Center, University of Liverpool. The aims of the workshop were to (1) discuss our current understanding of the genetic, clinical, and chemical basis of small molecule drug hypersensitivity, (2) highlight the current status of assays that might be developed to predict potential drug immunogenicity, and (3) identify the limitations, knowledge gaps, and challenges that limit the use of these assays and utilize the knowledge gained from the workshop to develop a pathway to establish new and improved assays that better predict drug-induced hypersensitivity reactions during the early stages of drug development. This perspective reviews the clinical and immuno-logical bases of drug hypersensitivity and summarizes various experts' views on the different topics covered during the meeting.
Author(s): Ogese MO, Ahmed S, Alferivic A, Betts CJ, Dickinson A, Faulkner L, French N, Gibson A, Hirschfield GM, Kammuller M, Meng XL, Martin SF, Musette P, Norris A, Pirmohamed M, Park BK, Purcell AW, Spraggs CF, Whritenour J, Naisbitt DJ
Publication type: Article
Publication status: Published
Journal: Chemical Research in Toxicology
Year: 2017
Volume: 30
Issue: 1
Pages: 239-259
Print publication date: 17/01/2017
Online publication date: 02/11/2016
Acceptance date: 02/04/2016
ISSN (print): 0893-228X
ISSN (electronic): 1520-5010
Publisher: American Chemical Society
URL: http://dx.doi.org/10.1021/acs.chemrestox.6b00333
DOI: 10.1021/acs.chemrestox.6b00333
Altmetrics provided by Altmetric