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Sensing and actuating electrophysiological activity on brain tissue and neuronal cultures with a high-density CMOS-MEA

Lookup NU author(s): Professor Evelyne SernagorORCiD


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Multielectrode arrays (MEAs) for electrophysiological studies in neuroscience can nowadays be realized with Complementary Metal Oxide Semiconductor (CMOS) technology to provide large active areas with several thousands of simultaneously recording microelectrodes and electrode densities with inter-electrode separations approaching cellular sizes. This provides spatial and temporal resolutions to literally image electrophysiological activity propagations. Here, we focus on the achieved sensing capabilities of a 64×64 electrode array as well as on the actuation performances of a novel CMOS-chip integrating 16 electrodes for electrical stimulation. We report and discuss our recent results obtained from neuronal cell cultures, brain slices and mouse retina preparations. © 2013 IEEE.

Publication metadata

Author(s): Maccione A, Simi A, Nieus T, Gandolfo M, Imfeld K, Ferrea E, Sernagor E, Berdondini L

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Year of Conference: 2013

Pages: 752-755

Online publication date: 10/10/2013

Publisher: IEEE


DOI: 10.1109/Transducers.2013.6626875

Library holdings: Search Newcastle University Library for this item

ISBN: 9781467359818