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Lookup NU author(s): Professor Kenn Gerdes
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© 2013 Springer-Verlag Berlin Heidelberg. All rights reserved. RelBE of Escherichia coli K-12 is a paradigm TA locus. Here, I describe the discovery of relBE and review the genetic, physiological, biochemical and structural analyses that have led to important insights into TA biology. Five relBE homologues of K-12 are also described while the 6th (mqsRA) is treated in a separate Chapter. Finally, a discussion of the possible biological functions of relBE and other type II TA loci sets the stage for future work on prokaryotic type II TA loci.
Author(s): Gerdes K
Publication type: Book Chapter
Publication status: Published
Book Title: Prokaryotic Toxin-Antitoxins
Year: 2013
Pages: 69-92
Print publication date: 01/11/2013
Online publication date: 19/10/2012
Publisher: Springer-Verlag Berlin Heidelberg
URL: https://doi.org/10.1007/978-3-642-33253-1_5
DOI: 10.1007/978-3-642-33253-1_5
Library holdings: Search Newcastle University Library for this item
ISBN: 9783642332531