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Lookup NU author(s): Jane Eastham,
Emeritus Professor Robin Seymour
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Local drug delivery systems (LDDs) are mainly used as adjuncts to root surface instrumentation (RSI) in the management of periodontal disease. A range of antibacterial agents have been used for this purpose and include the tetracyclines, chlorhexidine, metronidazole, azithromycin, clarithromycin and moxifloxacin. More recently, other non-antibacterial agents have been incorporated into local delivery devices and include simvastatin, metformin and alendronate. This paper will review the effectiveness of such agents when used as an adjunct to conventional non-surgical periodontal therapy.
Author(s): Eastham JE, Seymour RA
Publication type: Article
Publication status: Published
Journal: Dental Update
Print publication date: 01/11/2014
Acceptance date: 01/01/1900
ISSN (print): 0305-5000
Publisher: George Warman Publications