SAW assisted blood/plasma separation in microchannel with constriction-expansion transition

Zhang, J; Wei, X; Ren, J; Xue, X; Jiang, Z

doi:10.1109/NEMS.2015.7147379

SAW assisted blood/plasma separation in microchannel with constriction-expansion transition

Lookup NU author(s): Dr Xiang Xue

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Abstract

© 2015 IEEE. A surface acoustic wave (SAW) based microfluidic device for human blood plasma separation has been proposed and experimentally demonstrated. The microchannel consists of a constriction-expansion section and a bifurcation channel. The effect of constriction-expansion transition on the blood separation has been investigated with and without SAW. An acoustic power of 20.43 dBm is found enough for plasma isolation from 50× diluted human blood at a flow rate of 0.006μL/min. Higher acoustic power is required for the blood separation at higher flow rate. A diagram of combined working conditions is obtained for guiding the successful blood/plasma separation in the microfluidic chip of given design.