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Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients with Severe Malaria in Europe: The TropNet Severe Malaria Study

Lookup NU author(s): Dr Matthias Schmid

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Abstract

© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care unit and hospital treatment in European patients with imported severe malaria.

Publication metadata

Author(s): Kurth F, Develoux M, Mechain M, Clerinx J, Antinori S, Gjorup IE, Gascon J, Morch K, Nicastri E, Ramharter M, Bartoloni A, Visser L, Rolling T, Zanger P, Calleri G, Salas-Coronas J, Nielsen H, Just-Nubling G, Neumayr A, Hachfeld A, Schmid ML, Antonini P, Pongratz P, Kern P, Saraiva Da Cunha J, Soriano-Arandes A, Schunk M, Suttorp N, Hatz C, Zoller T

Publication type: Article

Publication status: Published

Journal: Clinical Infectious Diseases

Year: 2015

Volume: 61

Issue: 9

Pages: 1441-1444

Print publication date: 01/11/2015

Online publication date: 17/07/2015

Acceptance date: 08/07/2015

ISSN (print): 1058-4838

ISSN (electronic): 1537-6591

Publisher: Oxford University Press

URL: http://doi.org/10.1093/cid/civ575

DOI: 10.1093/cid/civ575

PubMed id: 26187021

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