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Lookup NU author(s): Dr Ricardo Martins Gouveia,
Professor Che Connon
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© 2016, 2010 Elsevier Ltd. All rights reserved. The present chapter sets out to define the usefulness of collagen in corneal tissue engineering. Briefly outlining collagen's role in the normal cornea and its biochemistry, the chapter goes on to describe recent approaches to fabricating collagen-based corneal constructs taking in both top-down and bottom-up rational design, as well as synthetic alternatives to collagen. Particular attention is paid to both decellularization and recellularization techniques, as well as the resulting changes in the collagen gel's ultrastructural, biophysical, and biochemical properties.
Author(s): Gouveia RM, Connon CJ
Publication type: Book Chapter
Publication status: Published
Book Title: Biomaterials and Regenerative Medicine in Ophthalmology: Second Edition
Print publication date: 20/04/2016
Online publication date: 29/04/2016
Acceptance date: 01/01/2016
Series Title: Woodhead Publishing Series in Biomaterials
Publisher: Elsevier Inc.
Place Published: Cambridge
Notes: Hardback ISBN 9780081001479
Library holdings: Search Newcastle University Library for this item