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Prevalence and management of recurrent respiratory papillomatosis (RRP) in the UK: cross-sectional study

Lookup NU author(s): Kim Keltie, Dr Andrew SimsORCiD, Steven Powell



This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).


© 2016 The Authors. Clinical Otolaryngology Published by John Wiley & Sons Ltd Objectives: To estimate the number of patients with recurrent respiratory papillomatosis currently managed in secondary and tertiary health care in the UK and the frequency of its treatment with radiofrequency cold ablation (Coblation™). Design: Cross-sectional survey of ENT consultants in the UK with validation using Hospital Episode Statistics (HES) inpatient data. Setting: Online survey. Participants: ENT consultants in the UK. Main outcome measures: Number of recurrent respiratory papillomatosis patients currently managed in acute care in the UK and frequency of use of Coblation. Results: A total of 283 ENT consultants from 128 UK NHS healthcare trusts and health boards completed the online survey. Responses were received from 86% of surveyed organisations, and an estimated 45% of all ENT consultants in UK. The estimated number of recurrent respiratory papillomatosis patients from the cross-sectional survey was 918 (at August 2015) which included 730 patients in England. The number of recurrent respiratory papillomatosis patients in England estimated from Hospital Episode Statistics (2014/15 financial year) was up to 741. A total of 42 Coblation procedures conducted in the UK were identified from the cross-sectional survey; 36 were conducted in England compared with 34 identified from Hospital Episode Statistics. Conclusions: The numbers of recurrent respiratory papillomatosis patients and Coblation procedures identified in England from a cross-sectional survey and Hospital Episode Statistics were in broad agreement. Our study estimated 1.42 recurrent respiratory papillomatosis patients per 100 000 in the general UK population. We also estimated that Coblation procedures accounted for 3% of interventional treatments conducted in the UK recurrent respiratory papillomatosis population.

Publication metadata

Author(s): Donne AJ, Keltie K, Cole H, Sims AJ, Patrick H, Powell S

Publication type: Article

Publication status: Published

Journal: Clinical Otolaryngology

Year: 2017

Volume: 42

Issue: 1

Pages: 86-91

Print publication date: 01/02/2017

Online publication date: 21/05/2016

Acceptance date: 25/04/2016

Date deposited: 11/05/2017

ISSN (print): 1749-4478

ISSN (electronic): 1749-4486

Publisher: Wiley-Blackwell


DOI: 10.1111/coa.12683


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