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Lookup NU author(s): Dr Yu-Tzu Wu,
Professor Fiona Matthews
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2016 American Journal of Preventive Medicine. Introduction: Built environment features have been related to behavior modification and might stimulate cognitive activity with a potential impact on cognitive health in later life. This study investigated cross-sectional associations between features of land use and cognitive impairment and dementia, and also explored urban and rural differences in these associations. Methods: Postcodes of the 7,505 community-based participants (aged ≥65 years) in the Cognitive Function and Ageing Study II (collected in 2008-2011) were linked to environmental data from government statistics. Multilevel logistic regression investigated associations between cognitive impairment (defined as Mini-Mental State Examination score ≤25) and dementia (Geriatric Mental Status and Automatic Geriatric Examination for Computer-Assisted Taxonomy organicity level ≥3) and land use features, including natural environment availability and land use mix, fitting interaction terms with three rural/urban categories. Data were analyzed in 2015. Results: Associations between features of land use and cognitive impairment were not linear. After adjusting for individual-level factors and area deprivation, living in areas with high land use mix was associated with a nearly 30% decreased odds of cognitive impairment (OR=0.72, 95% CI=0.58, 0.89). This was similar, yet non-significant, for dementia (OR=0.70, 95% CI=0.46, 1.06). In conurbations, living in areas with high natural environment availability was associated with 30% reduced odds of cognitive impairment (OR=0.70, 95% CI=0.50, 0.97). Conclusions: Non-linear associations between features of land use and cognitive impairment were confirmed in this new cohort of older people in England. Both lack of and overload of environmental stimulation may be detrimental to cognition in later life.
Author(s): Wu Y-T, Prina AM, Jones A, Matthews FE, Brayne C
Publication type: Article
Publication status: Published
Journal: American Journal of Preventive Medicine
Print publication date: 01/07/2017
Online publication date: 09/01/2017
Acceptance date: 01/01/1900
Date deposited: 07/04/2017
ISSN (print): 0749-3797
ISSN (electronic): 1873-2607
Publisher: Elsevier Inc.
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