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Lookup NU author(s): Dr Javed Ahmed
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© 2017 Elsevier Inc. Ageing is related to complex molecular, inflammatory and biochemical changes that affect coronary pathology and often lead to coronary artery disease and cardiovascular events. Intravascular imaging is considered as the ideal technique to study coronary plaque morphology and assess its burden. Over the recent years several studies have been performed that investigated the association between pathophysiological mechanisms that promote vascular ageing and plaque morphology. In addition, several reports have compared plaque pathology in different age groups and a few studies included serial intravascular imaging to assess changes in the atheroma burden and compositional characteristics of the plaque. This review article summarizes the evidence derived from intravascular imaging studies about the implications of vascular ageing on coronary artery morphology and discusses the potential of coronary imaging in assessing atherosclerotic evolution.
Author(s): Bourantas CV, Crake T, Zhang Y-J, Ozkor M, Ahmed J, Garcia-Garcia HM, Serruys PW
Publication type: Article
Publication status: Published
Journal: Experimental Gerontology
Print publication date: 01/08/2018
Online publication date: 15/05/2017
Acceptance date: 14/05/2017
ISSN (print): 0531-5565
ISSN (electronic): 1873-6815
Publisher: Elsevier Inc.
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