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Intravascular imaging in cardiovascular ageing

Lookup NU author(s): Dr Javed Ahmed

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Abstract

© 2017 Elsevier Inc. Ageing is related to complex molecular, inflammatory and biochemical changes that affect coronary pathology and often lead to coronary artery disease and cardiovascular events. Intravascular imaging is considered as the ideal technique to study coronary plaque morphology and assess its burden. Over the recent years several studies have been performed that investigated the association between pathophysiological mechanisms that promote vascular ageing and plaque morphology. In addition, several reports have compared plaque pathology in different age groups and a few studies included serial intravascular imaging to assess changes in the atheroma burden and compositional characteristics of the plaque. This review article summarizes the evidence derived from intravascular imaging studies about the implications of vascular ageing on coronary artery morphology and discusses the potential of coronary imaging in assessing atherosclerotic evolution.

Publication metadata

Author(s): Bourantas CV, Crake T, Zhang Y-J, Ozkor M, Ahmed J, Garcia-Garcia HM, Serruys PW

Publication type: Article

Publication status: Published

Journal: Experimental Gerontology

Year: 2018

Volume: 109

Pages: 31-37

Print publication date: 01/08/2018

Online publication date: 15/05/2017

Acceptance date: 14/05/2017

ISSN (print): 0531-5565

ISSN (electronic): 1873-6815

Publisher: Elsevier Inc.

URL: https://doi.org/10.1016/j.exger.2017.05.011

DOI: 10.1016/j.exger.2017.05.011

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