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Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self surface-selective regulation of complement activation

Lookup NU author(s): Dr Edwin Wong, Dr Yi Yang, Professor Kevin MarchbankORCiD, Professor David KavanaghORCiD

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This is the authors' accepted manuscript of an article that has been published in its final definitive form by American Society for Biochemistry and Molecular Biology, Inc., 2017.

For re-use rights please refer to the publisher's terms and conditions.


Publication metadata

Author(s): Kerr H, Wong E, Makou E, Yang Y, Marchbank K, Kavanagh D, Richards A, Herbert A, Barlow P

Publication type: Article

Publication status: Published

Journal: Journal of Biological Chemistry

Year: 2017

Volume: 292

Pages: 13345-13360

Print publication date: 11/08/2017

Online publication date: 21/06/2017

Acceptance date: 21/06/2017

Date deposited: 09/08/2017

ISSN (print): 0021-9258

ISSN (electronic): 1083-351X

Publisher: American Society for Biochemistry and Molecular Biology, Inc.

URL: https://doi.org/10.1074/jbc.M117.795088

DOI: 10.1074/jbc.M117.795088

PubMed id: 28637873


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Funding

Funder referenceFunder name
BB/024403/1
MRC
RPG-2015-109

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