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Lookup NU author(s): Dr Ilona Obara,
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
© 2016 Elsevier Ltd The first studies of histamine and diabetes date back to the 1950s. Since that time the involvement of histamine in diabetes was related to its well known vasoactive properties and permeability leakage effects. In particular, the first evidence for a correlation between histamine and diabetes arose in 1989 when an increase in plasma and leucocyte histamine content was observed. Limited independent evidence followed in the subsequent two decades, focusing on both histamine glyceamic control and macro- and microvascular complications of diabetes. However, recent observations have sparked the question whether it is time to reconsider the functional contribution of histamine in diabetes. We reveal an interesting upsurge in the field which provides scope for new insights into the role of histamine in diabetes.
Author(s): Pini A, Obara I, Battell E, Chazot PL, Rosa AC
Publication type: Article
Publication status: Published
Journal: Pharmacological Research
Print publication date: 01/09/2016
Online publication date: 22/06/2016
Acceptance date: 21/06/2016
Date deposited: 31/01/2019
ISSN (print): 1043-6618
ISSN (electronic): 1096-1186
Publisher: Academic Press
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