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Lookup NU author(s): Dr Rhys ThomasORCiD
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© 2015 Elsevier Inc. It is well recognized that mood disorders and epilepsy commonly co-occur. Despite this, our knowledge regarding the relationship between epilepsy and bipolar disorder is limited. Several shared features between the two disorders, such as their episodic nature and potential to run a chronic course, and the efficacy of some antiepileptic medications in the prophylaxis of both disorders, are often cited as evidence of possible shared underlying pathophysiology. The present paper aims to review the bidirectional associations between epilepsy and bipolar disorder, with a focus on epidemiological links, evidence for shared etiology, and the impact of these disorders on both the individual and wider society. Better recognition and understanding of these two complex disorders, along with an integrated clinical approach, are crucial for improved evaluation and management of comorbid epilepsy and mood disorders.
Author(s): Knott S, Forty L, Craddock N, Thomas RH
Publication type: Review
Publication status: Published
Journal: Epilepsy and Behavior
Issue: Part A
Print publication date: 01/11/2015
Online publication date: 25/08/2015
Acceptance date: 02/07/2015
ISSN (print): 1525-5050
ISSN (electronic): 1525-5069
Publisher: Academic Press Inc.
PubMed id: 26316422