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Lookup NU author(s): Dr Keng Wooi Ng,
Dr Wing Man Lau
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Synergistic combinations of chemical penetration enhancers are important considerations in drug formulation because they can greatly influence transdermal drug delivery, positively or negatively. This chapter describes how synergistic actions between chemical penetration enhancers can be defined, discovered and measured. The chapter considers literature reports where both positive and negative synergism between chemical penetration enhancers have been described. The underlying mechanisms of action that result in enhancer synergy are also discussed.
Author(s): Ng KW, Lau WM, Williams AC
Editor(s): Dragicevic, N; Maibach, H
Publication type: Book Chapter
Publication status: Published
Book Title: Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement
Print publication date: 01/01/2015
Acceptance date: 01/01/2014
Place Published: Berlin, Heidelberg
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