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Sentinel node biopsy for diagnosis of pelvic lymph node involvement in early stage cervical cancer

Lookup NU author(s): Dr Stuart Rundle, Dr Kristoffer Halvorsrud, Dr Ann Fisher, Andrew Bryant, Ali Kucukmetin



© 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To assess the diagnostic accuracy of sentinel lymph node biopsy in the identification of lymph node involvement in patients with early stage cervical cancer (Stage IA2 to IIA). We will first explore the impact of major factors for heterogeneity such as tumour size, FIGO stage and timing between application, detection of tracers, tracer substance used, surgical approach, experience of the operator and use of histological ultra-staging techniques. Then, we may consider other factors such as previous treatment to the cervix (including conisation), patient age and body mass index, as these have previously been suggested as possible factors associated with success or failure of sentinel node identification (Sinno 2014; Tanner 2015; Wuntakal 2015).

Publication metadata

Author(s): Rundle S, Halvorsrud K, Bizzarri N, Ratnavelu NDG, Fisher AD, Ang C, Bryant A, Naik R, Kucukmetin A

Publication type: Article

Publication status: Published

Journal: Cochrane Database of Systematic Reviews

Year: 2017

Volume: 2017

Issue: 12

Online publication date: 18/12/2017

Acceptance date: 02/04/2016

Date deposited: 11/01/2018

ISSN (electronic): 1469-493X

Publisher: John Wiley and Sons Ltd


DOI: 10.1002/14651858.CD007925.pub2

Notes: Version 3.


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