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A Scalable Optoelectronic Neural Probe Architecture with Self-Diagnostic Capability

Lookup NU author(s): Professor Patrick Degenaar

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Abstract

There is a growing demand for the development of new types of implantable optoelectronics to support both basic neuroscience and optogenetic treatments for neurological disorders. Target specification requirements include multi-site optical stimulation, programmable radiance profile, safe operation, and miniaturisation. It is also preferable to have a simple serial interface rather than large numbers of control lines. This paper demonstrates an optrode structure comprising of a standard Complementary Metal-Oxide-Semiconductor (CMOS) process with 18 optical stimulation drivers. Furthermore, diagnostic sensing circuitry is incorporated to determine the long-term functionality of the photonic elements. A digital control system is incorporated to allow independent multisite control and serial communication with external control units.

Publication metadata

Author(s): Zhao Hubin, Soltan Ahmed, Maaskant Pleun, Dong Na, Sun Xiaohan, Degenaar Patrick

Publication type: Article

Publication status: Published

Journal: IEEE Transactions on Circuits and Systems I - Regular papers

Year: 2018

Volume: 65

Issue: 8

Pages: 2431-2442

Print publication date: 01/08/2018

Online publication date: 24/01/2018

Acceptance date: 22/12/2017

Date deposited: 10/01/2018

ISSN (print): 1549-8328

ISSN (electronic): 1558-0806

Publisher: Institute of Electrical and Electronics Engineers

URL: https://doi.org/10.1109/TCSI.2018.2792219

DOI: 10.1109/TCSI.2018.2792219

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