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Outcomes of infants with a birthweight less than or equal to 500 g in Northern England: 15 years experience

Lookup NU author(s): Dr Nicola Miller, Dr Martin Ward Platt, Dr Sundeep Harigopal


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©2017 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd Aim: We aimed to evaluate mortality and short-term neonatal morbidity of babies born ≤500 g cared for in the Northern Neonatal Network over a 15-year period. Method: Using regional databases, we identified all live-born babies ≥22 weeks gestation and ≤500 g, in North East England and North Cumbria from 1998 to 2012. We quantified major neonatal morbidities and survival to one year. Results: We identified 104 live-born babies ≥22 weeks gestation and ≤500 g (birth prevalence 0.22/1000), of which 49 were admitted for intensive care. Overall one-year survival was 11%, but survival for those receiving intensive care was 22%. There was significant short-term neonatal morbidity in survivors, in particular retinopathy of prematurity and chronic lung disease. Conclusion: Survival of babies born weighing ≤500 g in this cohort remains poor despite advances in neonatal care, with considerable short-term neonatal morbidity in survivors. This could be due to a combination of attitudes and a rather conservative approach towards resuscitation and intensive care, and the intrinsic nature of these tiny babies.

Publication metadata

Author(s): Gillone J, Banait N, Miller N, Ward Platt M, Harigopal S

Publication type: Article

Publication status: Published

Journal: Acta Paediatrica

Year: 2018

Volume: 107

Issue: 2

Pages: 223-226

Print publication date: 01/02/2018

Online publication date: 17/09/2017

Acceptance date: 15/08/2017

ISSN (print): 0803-5253

ISSN (electronic): 1651-2227

Publisher: John Wiley & Sons Ltd


DOI: 10.1111/apa.14024


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