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Lookup NU author(s): Professor Alan Bull,
Professor Michael Goodfellow
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© 2018 Japan Antibiotics Research Association Bio-guided fractionation of the culture broth extract of Streptomyces asenjonii strain KNN 42.f recovered from an extreme hyper-arid Atacama Desert soil in northern Chile led to the isolation of three new bioactive β-diketones; asenjonamides A–C (1–3) in addition to the known N-(2-(1H-indol-3-yl)-2-oxoethyl)acetamide (4), a series of bioactive acylated 4-aminoheptosyl-β-N-glycosides; spicamycins A–E (5–9), and seven known diketopiperazines (10–16). All isolated compounds were characterized by HRESIMS and NMR analyses and tested for their antibacterial effect against a panel of bacteria.
Author(s): Abdelkader MSA, Philippon T, Asenjo JA, Bull AT, Goodfellow M, Ebel R, Jaspars M, Rateb ME
Publication type: Article
Publication status: Published
Journal: Journal of Antibiotics
Print publication date: 01/04/2018
Online publication date: 23/01/2018
Acceptance date: 02/11/2017
ISSN (print): 0021-8820
ISSN (electronic): 1881-1469
Publisher: Nature Publishing Group
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