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Progress in mitochondrial replacement therapies

Lookup NU author(s): Professor Mary Herbert, Emeritus Professor Doug Turnbull


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© 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Mitochondrial DNA is maternally inherited, and pathogenic mutations cause a range of life-limiting conditions. Recent studies indicate that transmission of pathogenic mutations may be prevented by reproductive technologies designed to replace the mitochondria in eggs from affected women.

Publication metadata

Author(s): Herbert M, Turnbull D

Publication type: Review

Publication status: Published

Journal: Nature Reviews Molecular Cell Biology

Year: 2018

Volume: 19

Issue: 2

Pages: 71-72

Online publication date: 23/01/2018

Acceptance date: 02/04/2016

ISSN (print): 1471-0072

ISSN (electronic): 1471-0080

Publisher: Nature Publishing Group


DOI: 10.1038/nrm.2018.3