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Lookup NU author(s): Dr Vasilios Andriotis
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Small-molecule probes can be used in conjunction with traditional genetic and biochemical methods to gain a better understanding of metabolic processes. Chemical genetics has been significantly utilized in the areas of plant hormones and herbicide development; chemical probes have become established tools for the dissection of signaling pathways and for agrochemical applications. Herein we discuss the use of small-molecule probes in the field of plant carbohydrate research, with particular focus on noncovalent probes. The use of direct inhibitors such as iminosugars, metabolic incorporation of labels, and indirect inhibition of carbohydrate processing have helped provide insight into key areas of plant carbohydrate metabolism, including starch, cell wall, glycoprotein and glycolipid synthesis, degradation, and spatial organization.
Author(s): Rugen MD, Andriotis VME, Field RA
Editor(s): Reedijk, J
Publication type: Book Chapter
Publication status: Published
Book Title: Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Online publication date: 24/03/2017
Acceptance date: 25/01/2017
Library holdings: Search Newcastle University Library for this item