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Effect of β -lactamases associated to the resistance of β -lactam antibiotics on the treatment of wastewater

Lookup NU author(s): Catalina Rodriguez, Professor David GrahamORCiD

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Abstract

© 2018 Elsevier Ltd. Antibiotics are drugs used on both animals and humans. However, when their residues or metabolites are released into the environment, it can cause microbial resistance in water bodies, including wastewater treatment plants. In this study, extended spectrum β-lactamases (ESBLs) were monitored in an anaerobic-aerobic combined biological treatment system. The enzymes Oxacillinase (OXA), Cefotaximases (CTX) and New Delhi metallo-β-lactamase (NDM-1) were added to the treatment and analyzed by qPCR (Quantitative Polymerase Chain Reaction) and plate count using a selective medium. Quantification of the effect of adding these enzymes was performed before, during and after they were added in order to establish the behavior of the treatment system under three different conditions. Anaerobic reactors proved more efficient at treating wastewater containing the β-lactamases OXA, CTX and NDM-1 than the ASP3 aerobic reactor that was working individually. However, an anaerobic-aerobic treatment train was much more effective at removing organic matter, even in the presence of β-lactamase.

Publication metadata

Author(s): Rodriguez DC, Ahammad ZS, Penuela GA, Graham DW

Publication type: Article

Publication status: Published

Journal: Journal of Environmental Chemical Engineering

Year: 2020

Volume: 8

Issue: 1

Print publication date: 01/02/2020

Online publication date: 06/03/2018

Acceptance date: 05/03/2018

ISSN (electronic): 2213-3437

Publisher: Elsevier Ltd

URL: https://doi.org/10.1016/j.jece.2018.03.006

DOI: 10.1016/j.jece.2018.03.006

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