Toggle Main Menu Toggle Search

Open Access padlockePrints

Accuracy of left atrial bipolar voltages obtained by ConfiDENSE multielectrode mapping in patients with persistent atrial fibrillation

Lookup NU author(s): Dr Moloy Das, Matthew Shaw


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


© 2018 Wiley Periodicals, Inc. Introduction: The ConfiDENSE™ module (Carto3 v4) allows rapid annotation of endocardial electrograms acquired by multielectrode (ME) mapping. However, its accuracy in assessing atrial voltages is unknown. Methods and results: Two ConfiDENSE™ left atrial voltage maps were created during continuous pacing in 20 patients undergoing catheter ablation for persistent AF using a ME lasso catheter and a contact force (CF) sensing ablation catheter. The automated tissue proximity indicator (TPI) filter was then applied to the ME map to yield a TPI map. Reference maps (RM) were created offline by a blinded observer by manually assessing all points against fidelity criteria. Bipolar voltages and proportion of low voltage points (< 0.5 mV) derived from the ME, CF, and TPI maps were compared with those derived from the RM. Note that 853 ± 365 points, 252 ± 184 points, and 144 ± 73 were collected for ME, TPI, and CF maps, respectively, and 429 ± 153 points were included in the RM. Voltages with CF and TPI maps were similar to those with RM (1.57 ± 0.47 mV vs. 1.63 ± 0.31 mV, P = 0.57 and 1.50 ± 0.38 mV vs. 1.63 ± 0.31 mV, P = 0.07, respectively), whereas ME maps showed a significantly lower mean voltage (1.00 ± 0.22 mV, P < 0.001). As compared to RM maps (17 ± 8%), low voltage points were significantly overestimated by the ME maps (50 ± 9% (P < 0.001) and TPI maps (28 ± 13% (P < 0.001), but not by the CF maps (22 ± 14%, P = 0.17). Conclusion: Application of the TPI filter to ConfiDENSE maps significantly increases the quality of the voltage data, conserving a reasonable point density, but still overestimates low voltage points as compared to CF-sensing maps or maps reviewed manually.

Publication metadata

Author(s): Maille B, Das M, Hussein A, Shaw M, Chaturvedi V, Morgan M, Ronayne C, Snowdon RL, Gupta D

Publication type: Article

Publication status: Published

Journal: Journal of Cardiovascular Electrophysiology

Year: 2018

Volume: 29

Issue: 6

Pages: 881-888

Print publication date: 01/06/2018

Online publication date: 05/03/2018

Acceptance date: 20/02/2018

ISSN (print): 1045-3873

ISSN (electronic): 1540-8167

Publisher: Wiley-Blackwell Publishing Inc.


DOI: 10.1111/jce.13472


Altmetrics provided by Altmetric