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Thrombocytopenia after aortic valve replacement: Comparison between sutureless perceval s valve and perimount magna ease bioprosthesis

Lookup NU author(s): Dr Stephan Schueler, T Pillay

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

© 2018, Sociedade Brasileira de Cirurgia Cardiovascular. All rights reserved. Introduction: The incidence of postoperative thrombocytopenia after aortic valve replacement (AVR) with the Perceval S Sutureless bioprosthesis remains unclear. The aim of this study was to report thrombocytopenia associated with the use of sutureless AVR. Methods: The data was collected retrospectively for patients who had isolated AVR with sutureless Perceval S valve (Group A: 72 patients) and was compared with patients who underwent isolated sutured AVR with Perimount Magna Ease Bioprosthesis (Group B: 101 patients) in our institution between June 2014 and January 2017. Results: Cardiopulmonary bypass and cross-clamp time were significantly shorter in group A. Maximum drop in platelet count was 58% mean (day 2.3) in group A versus 44% mean (day 1.7) in group B (P=0.0001). Absolute platelet count on postoperative day 1-6 in group A was significantly less than in group B (P≤0.05). Platelet count recovered to preoperative value in 44% patients in group B versus only in 26% patients in group A at discharge (P=0.018). Moderate thrombocytopenia occurs more often in group A (41% vs. 26%) (P=0.008) while severe thrombocytopenia (<50 x 109) was observed in 6% in group A but never in group B. Platelets (P=0.007) and packed red blood cells (P=0.009) transfusion was significantly higher in the group A. Conclusion: The implantation of sutureless Perceval aortic valves was associated with a significant drop in platelet count postoperatively with slow recovery and higher platelets and packed red blood cells transfusion requirements. A prospective randomised trial is needed to confirm our findings.

Publication metadata

Author(s): Mujtaba SS, Ledingham S, Shah AR, Schueler S, Clark S, Pillay T

Publication type: Article

Publication status: Published

Journal: Brazilian Journal of Cardiovascular Surgery

Year: 2018

Volume: 33

Issue: 2

Pages: 169-175

Print publication date: 01/04/2018

Acceptance date: 06/09/2017

Date deposited: 12/06/2018

ISSN (print): 0102-7638

ISSN (electronic): 1678-9741

Publisher: Sociedade Brasileira de Cirurgia Cardiovascular

URL: https://doi.org/10.21470/1678-9741-2017-0157

DOI: 10.21470/1678-9741-2017-0157

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