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Data on Manuka Honey/Gellan Gum composite hydrogels for cartilage repair

Lookup NU author(s): Dr Piergiorgio Gentile, Dr Ana Ferreira-Duarte

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Abstract

© 2018 The Authors This work contains original data supporting our research paper “Antibacterial effectiveness meets improved mechanical properties: Manuka Honey/Gellan Gum composite hydrogels for cartilage repair”, Bonifacio et al., in press [1], in which innovative composite hydrogels, based on Gellan Gum/Manuka honey/Halloysite nanotubes were described as biomaterials for cartilage regeneration. Here the composites were further examined by means of Fourier Transform Infrared Spectroscopy, in Attenuated Total Reflectance mode (FT-IR/ATR). Materials devoted to cartilage replacement must possess adequate fluid permeability and lubricating capability, therefore, a deeper investigation on water uptake kinetics of freeze-dried specimens up to 21 days in PBS was carried out. Moreover, since the degradation rate of a biomaterial plays a pivotal role in tissue engineering, weight loss measurements of the prepared hydrogels were performed in simulated synovial fluid, in phosphate buffer solution (PBS) and in lysozyme. Scanning Electron Microscopy images provide insight into the morphology of the freeze-dried samples. Finally, additional information on Staphylococcus aureus and Staphylococcus epidermidis ability to adhere onto the prepared hydrogel composites in short times were obtained, as well as the chondrogenic potential of the composites assessed by SDS-PAGE followed by Coomassie blue gel staining.


Publication metadata

Author(s): Bonifacio MA, Cometa S, Cochis A, Gentile P, Ferreira AM, Azzimonti B, Procino G, Ceci E, Rimondini L, De Giglio E

Publication type: Article

Publication status: Published

Journal: Data in Brief

Year: 2018

Volume: 20

Pages: 831-839

Online publication date: 30/08/2018

Acceptance date: 24/08/2018

ISSN (electronic): 2352-3409

Publisher: Elsevier Inc.

URL: https://doi.org/10.1016/j.dib.2018.08.155

DOI: 10.1016/j.dib.2018.08.155

Data Source Location: http://dx.doi.org/10.17634/122951-8


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