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Lookup NU author(s): Dr Andrew Hall
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© Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ. Aim: To survey UK cellular pathology departments regarding their attitudes and practices relating to release of human tissue from their diagnostic archives for use in clinical trial research. Methods: A 30-item questionnaire was circulated to the National Cancer Research Institute's Cellular Molecular Pathology initiative and Confederation of Cancer Biobanks mailing lists. Responses were collected over a 10-month period from November 2016 to August 2017. Results: 38 departments responded to the survey, the majority of which regularly receive requests for tissue for research purposes. Most requests come from academia and financial support to facilitate tissue release comes from a variety of sources. A range of practices were reported in relation to selection of the most appropriate sample to release, consent checking, costing and governance frameworks. Conclusions: This survey demonstrates wide variation in practice across the UK and identifies barriers to release of human tissue for clinical trial research. Until we can overcome these obstacles, patient samples will remain inaccessible to research. Therefore, this study highlights the urgent need for clear and coordinated national guidance on this issue.
Author(s): Macklin PS, Hall A, Lee J, Hair J, Speirs V, Thomas GJ, Oien KA, Verrill C
Publication type: Article
Publication status: Published
Journal: Journal of Clinical Pathology
Year: 2018
Volume: 72
Issue: 1
Pages: 52-57
Print publication date: 01/01/2019
Online publication date: 01/10/2018
Acceptance date: 05/09/2018
ISSN (print): 0021-9746
ISSN (electronic): 1472-4146
Publisher: BMJ Publishing Group
URL: https://doi.org/10.1136/jclinpath-2018-205476
DOI: 10.1136/jclinpath-2018-205476
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