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Lookup NU author(s): Dr Charlie Tomson
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© Royal College of Physicians 2018. All rights reserved. The introduction of the term 'acute kidney injury' (AKI) along with an international classification scheme,1 caused some initial confusion, but most clinicians and many patients now understand that the term 'injury' denotes damage to the internal workings of the kidney, rather than physical trauma. However, of greater concern is the use of the term 'nephrotoxic' to include drugs that are, in most settings, nephroprotective. We argue that this imprecise terminology, unfortunately adopted by the National Institute for Health and Care Excellence (NICE) among others, is potentially harmful, and that the terms 'nephrotoxin' and 'nephrotoxic' should not be used to describe haemodynamically mediated and fully reversible effects of some drugs on excretory function.
Author(s): Jones M, Tomson C
Publication type: Review
Publication status: Published
Journal: Clinical Medicine
Year: 2018
Volume: 18
Issue: 5
Pages: 384-386
Print publication date: 01/10/2018
Acceptance date: 02/04/2018
ISSN (print): 1470-2118
ISSN (electronic): 1473-4893
Publisher: NLM (Medline)
URL: https://doi.org/10.7861/clinmedicine.18-5-384
DOI: 10.7861/clinmedicine.18-5-384
PubMed id: 30287431