Toggle Main Menu Toggle Search

Open Access padlockePrints

Global prevalence of molar incisor hypomineralisation

Lookup NU author(s): Greig Taylor



This is the authors' accepted manuscript of an article that has been published in its final definitive form by Nature Publishing Group, 2018.

For re-use rights please refer to the publisher's terms and conditions.


© 2018 British Dental Association. Data sources PubMed, Web of Science, ScienceDirect, Chinese Biological Medical Literature Database, Chinese Wanfang Database, Chinese National Knowledge Infrastructure and reference lists of key publications. Language restrictions were placed with inclusion of English and Chinese texts only. No date restrictions were applied. Study selection Original population-based studies that described the diagnostic criteria of MIH and provided prevalence data or sufficient information that could be used to calculate MIH prevalence. Data extraction and synthesis Two reviewers independently extracted the data. Meta-regression was done using a random effects model for parameters of age, gender and region. Heterogeneity was assessed using I2 statistic. Results Seventy studies were included that encompassed a total of 89,520 people and 10,823 cases of MIH. The pooled global prevalence of MIH was 14.2% (95% CI 12.6-15.8), with South America having the highest prevalence (18%; 95% CI 13.8-22.2) and Africa the lowest (10.9%; 95% CI 4.2-17.6). There was no significant difference between male and female participants. Prevalence of MIH amongst children ten years of age or younger (15.1%, 95% CI 12.1-18.2) was higher than older children (12.1%, 95% CI 8.0-16.3). Conclusions This meta-analysis showed the average global prevalence of MIH as 14.2%. Some geographic regions had higher than average prevalence, which could inform oral health policy in those areas.

Publication metadata

Author(s): Dave M, Taylor G

Publication type: Article

Publication status: Published

Journal: Evidence-Based Dentistry

Year: 2018

Volume: 19

Issue: 3

Pages: 78-79

Online publication date: 26/10/2018

Acceptance date: 02/04/2018

Date deposited: 15/01/2019

ISSN (print): 1462-0049

ISSN (electronic): 1476-5446

Publisher: Nature Publishing Group


DOI: 10.1038/sj.ebd.6401324

PubMed id: 30361661


Altmetrics provided by Altmetric