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Pathophysiology and Predictors of Bronchial Complications After Lung Transplantation

Lookup NU author(s): Professor John Dark

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Abstract

Copyright © 2018 Elsevier Inc. All rights reserved. Bronchial anastomotic breakdown was a major complication in the early days of lung transplantation. Their solution, achieved through an understanding of airway ischemia from the laboratory, was key to the initial clinical success. Subsequently, risk factors, such as prolonged ventilation in both donor and recipient, primary graft dysfunction, and recipient age, have emerged. Innovations, such as local tissue wrapping, telescoping the anastomosis, and bronchial artery revascularization, have not stood the test of time. The short donor bronchus, with a suture line at the level of the lobar bronchus carina, is a proven technique that should be adopted by surgeons.

Publication metadata

Author(s): Dark JH

Publication type: Review

Publication status: Published

Journal: Thoracic Surgery Clinics

Year: 2018

Volume: 28

Issue: 3

Pages: 357-363

Print publication date: 01/08/2018

Online publication date: 24/07/2018

Acceptance date: 02/04/2018

ISSN (print): 1547-4127

ISSN (electronic): 1558-5069

URL: https://doi.org/10.1016/j.thorsurg.2018.04.005

DOI: 10.1016/j.thorsurg.2018.04.005

PubMed id: 30054073

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