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Management of Urosepsis in 2018

Lookup NU author(s): Rob Pickard


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© 2018 European Association of Urology Despite optimal treatment, urosepsis has still high morbidity and mortality rates. An updated definition and classification system for sepsis have recently been introduced. Management of urosepsis comprises four major aspects: (1) early diagnosis, (2) early empiric intravenous antimicrobial treatment, (3) identification and control of complicating factors, and (4) specific sepsis therapy. The quick sequential organ failure assessment is replacing the systemic inflammatory response syndrome scoring for rapid identification of patients with urosepsis. Patient summary: Urosepsis is a serious, life-threatening complication of infections originating from the urinary tract. As urosepsis has a very high mortality rate, it is important that is quickly spotted and that appropriate treatment is swiftly begun. Imaging of urinary tract disorders has been shown to be useful in decreasing mortality from urosepsis, and in the future microbiology techniques may also prove useful. Given the severity of urosepsis and the associated risks, large efforts need to be made to prevent high-risk infections in hospitals with appropriate prevention measures, such as the early removal of catheters used whenever possible. Urosepsis is still a serious life-threatening complication of an infection originating from the urinary tract. Early and appropriate diagnosis of urosepsis is important to allow initiation of suitable treatment without delay.

Publication metadata

Author(s): Bonkat G, Cai T, Veeratterapillay R, Bruyere F, Bartoletti R, Pilatz A, Koves B, Geerlings SE, Pradere B, Pickard R, Wagenlehner FME

Publication type: Article

Publication status: Published

Journal: European Urology Focus

Year: 2019

Volume: 5

Issue: 1

Pages: 5-9

Print publication date: 01/01/2019

Online publication date: 15/11/2018

Acceptance date: 02/04/2018

ISSN (electronic): 2405-4569

Publisher: Elsevier BV


DOI: 10.1016/j.euf.2018.11.003


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