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Reducing cardiovascular risk in patients with type 2 diabetes mellitus

Lookup NU author(s): Professor Azfar Zaman, Dr Qaiser Aleem

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Abstract

© 2018 As obesity rates and life expectancies increase, diabetes mellitus continues to become more prevalent worldwide. Its complex pathophysiology is associated with micro- and macrovascular complications, with cardiovascular disease the leading cause of death in individuals with diabetes. Traditional anti-hyperglycaemic drugs have helped to improve glycaemic control without reducing cardiovascular complications, but novel agents such as sodium-glucose cotransporter (SGLT)-2 inhibitors and glucagon-like peptide (GLP)-1 receptor agonists have shown an effective reduction of adverse cardiovascular events. The management of diabetes focuses on reducing low-density lipoprotein-cholesterol, lowering blood pressure and keeping glycated haemoglobin within recommended limits. Pharmacological and lifestyle interventions should address all potential risk factors to improve cardiovascular outcomes in patients with diabetes.

Publication metadata

Author(s): Zaman AG, Aleem Q, Ahmed R

Publication type: Article

Publication status: Published

Journal: Medicine

Year: 2018

Volume: 47

Issue: 2

Pages: 72-76

Print publication date: 01/02/2019

Online publication date: 24/12/2018

Acceptance date: 02/04/2018

ISSN (print): 1357-3039

ISSN (electronic): 1365-4357

Publisher: Elsevier Espana

URL: https://doi.org/10.1016/j.mpmed.2018.11.012

DOI: 10.1016/j.mpmed.2018.11.012

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