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Terminal ileal intubation and biopsy in routine colonoscopy practice

Lookup NU author(s): Dr Laura Neilson, Professor Colin Rees


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© 2015 Informa UK, Ltd. This special report focuses on the current literature regarding the utility of terminal ileal (TI) intubation and biopsy. The authors reviewed the literature regarding the clinical benefit of TI intubation at the time of colonoscopy and also the evidence for TI intubation as a colonoscopy quality indicator. TI intubation is useful to identify ileal diseases such as Crohn's disease and additionally as a means of confirming colonoscopy completion when classical caecal landmarks are not confidently seen. Previous studies have demonstrated that TI intubation has variable yield but may be more useful in patients presenting with diarrhea. Reported rates of TI intubation at colonoscopy vary. The authors demonstrate that terminal ileoscopy is feasible in clinical practice and sometimes yields additional clinical information. Additionally it may be used as an indicator of colonoscopy completion. It may be particularly helpful when investigating patients with diarrhea, abnormalities seen on other imaging modalities and patients with suspected Crohn's disease. TIs reported as normal at endoscopy have a low yield when biopsied; however, biopsies from abnormal-looking TIs demonstrate a higher yield and have greater diagnostic value.

Publication metadata

Author(s): Neilson LJ, Bevan R, Panter S, Thomas-Gibson S, Rees CJ

Publication type: Review

Publication status: Published

Journal: Expert Review of Gastroenterology and Hepatology

Year: 2015

Volume: 9

Issue: 5

Pages: 567-574

Online publication date: 12/01/2015

Acceptance date: 12/01/2015

ISSN (print): 1747-4124

ISSN (electronic): 1747-4132

Publisher: Expert Reviews Ltd.


DOI: 10.1586/17474124.2015.1001744

PubMed id: 25582839