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Lookup NU author(s): Dr Sadegh NadimiORCiD
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Manipulating friction in particle engineering is of great interest in a wide range of manufacturing processes, but its characterisation is very challenging due to measurement difficulties. In bulk shear deformation, the interparticle interactions are directly affected by surface characteristics, including shape, roughness and adhesion. It is common practice to add a glidant to reduce friction in order to improve the powder flow and compaction. For example in pharmaceutical industry, this improves the drug delivery, in particular for the pulmonary route, but also in tabletting. However, the role of glidant as shape or roughness modifier and adhesion reducer is not well understood. In this study, the carrier with known shape in roughness and adhesion is coated with magnesium stearate (MgSt) using a high shear mixer. The spatial distribution of the glidant coating on the particle surfaces is quantified using energy-dispersive X-ray spectroscopy (EDX) under scanning electron microscopy (SEM) / electron probe micro-analyzer (EPMA) and time of flight secondary ion mass spectrometry (TOF-SIMS). The adhesion and friction of the coated particles are quantified using the Drop-Test Method and Nano-Tribometer. The insights into the role of glidant are fundamental for better understanding and control of particulate solids processes in many manufacturing operations.
Author(s): Nadimi S, Bai M, Inkson B, Neville A, Ghadiri M
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: International Congress on Particle Technology (PARTEC 2019)
Year of Conference: 2019
Acceptance date: 01/02/2019
Publisher: PARTEC
URL: https://www.partec.info/
