Toggle Main Menu Toggle Search

Open Access padlockePrints

The use of a single chamber leadless pacemaker for the treatment of cardioinhibitory vasovagal syncope

Lookup NU author(s): Dr Janet McComb



This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).


© 2019 The Authors Background: The use of pacemakers in the treatment of cardioinhibitory vasovagal syncope is controversial with a mixed message from the limited evidence base. Single chamber leadless pacemakers have been shown to be an effective alternative option to conventional pacemakers. Objective: This study examines the use of leadless pacemakers in a cardioinhibitory vasovagal population in the United Kingdom. Methods: Observational data on 32 patients implanted with the Micra Transcatheter Pacemaker System for vasovagal syncope are presented. Data was collected on implant indications, implant procedure and follow up data from 12 centres across the United Kingdom that had elected to use a Micra leadless pacemaker in this patient population. Results: 32 patients aged 37 ± 14 years (range 18 to 64 years) with 62% of the patients being female were recruited to the study. Vasovagal syncope was diagnosed clinically and with the support of Holter monitoring, tilt table testing and implantable loop recorders. The duration of symptoms was 8 ± 8 yrs. with an average frequency of syncope being 4 ± 6 times/year. The Micra pacemaker was successfully implanted in all patients with a major complication rate of 3.1%. Patients were followed up for 404 ± 237 days (range 63–928 days). At follow up 28 (87%) patients were free from symptoms. Conclusions: This observational study suggests that the use of a single chamber leadless pacemaker in the treatment of cardioinhibitory vasovagal syncope might be a reasonable clinical option.

Publication metadata

Author(s): Roberts PR, Pepper C, Rinaldi CA, Bates MGD, Thornley A, Somani R, Abozguia K, Harris S, Rao A, Pedersen M, McComb JM, Shepherd E, Moore P, Segal OR, Schilling RJ, Zaidi A

Publication type: Article

Publication status: Published

Journal: IJC Heart & Vasculature

Year: 2019

Volume: 23

Print publication date: 01/06/2019

Online publication date: 28/03/2019

Acceptance date: 17/03/2019

Date deposited: 09/04/2019

ISSN (print): 2352-9067

Publisher: Elsevier Ireland Ltd


DOI: 10.1016/j.ijcha.2019.100349


Altmetrics provided by Altmetric