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Development of a Flexible MIP-Based Biosensor Platform for the Thermal Detection of Neurotransmitters

Lookup NU author(s): Dr Marloes Peeters

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This is the authors' accepted manuscript of an article that has been published in its final definitive form by Materials Research Society, 2018.

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Abstract

Copyright © Materials Research Society 2017. We have developed high affinity Molecularly Imprinted Polymers (MIPs) for neurotransmitters such as dopamine, noradrenaline and caffeine. These polymer particles are mixed within the bulk of screen-printed ink allowing masss-producible bulk modified MIP Screen-Printed Electrodes (MIP-SPEs) to be realised. We have explored different SPE supporting surfaces, such as polyester, tracing paper and household-printing paper. The performance of those MIP-SPEs is studied using the Heat-Transfer Method (HTM), a patented thermal method. With the combination of screen-printing techniques and thermal detection, it is possible to develop a portable sensor platform that is capable of low-cost and straightforward detection of biomolecules on-site. In the future, this unique sensor architecture holds great promise for the use in biomedical devices.


Publication metadata

Author(s): Betlem K, Down MP, Foster CW, Akthar S, Eersels K, Van Grinsven B, Cleij TJ, Banks CE, Peeters M

Publication type: Article

Publication status: Published

Journal: MRS Advances

Year: 2018

Volume: 3

Issue: 28

Pages: 1569-1574

Online publication date: 05/01/2018

Acceptance date: 02/04/2016

Date deposited: 15/04/2019

ISSN (electronic): 2059-8521

Publisher: Materials Research Society

URL: https://doi.org/10.1557/adv.2017.634

DOI: 10.1557/adv.2017.634

Notes: Issue title: Biomaterials and Soft Materials


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