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Meaningful changes in the Short Form 12 physical and mental summary scores after total knee arthroplasty

Lookup NU author(s): James Holland, Craig Gerrand, Professor David Deehan


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© 2019 Elsevier B.V. Background: The aim of this study was to identify minimal clinically important difference (MCID), minimal important change (MIC) and minimal detectable change (MDC) for the Short Form (SF-) 12 physical and mental component summary (PCS, MCS) scores after total knee arthroplasty (TKA) using an anchor based methodology. Methods: During a 10-year period, 2589 TKA were performed. SF-12 PCS and MCS scores were recorded preoperatively and at one year postoperatively. At one year, patients were asked “How much did the knee replacement surgery improve the quality of your life?” Their response was recorded as: a great improvement, moderate improvement, little improvement, no improvement at all, or the quality of my life is worse. Patients recording a little (n = 211) and no (n = 115) were used to calculate the MCID and the MIC. The MDC90 was calculated using distribution based methods for the whole cohort. Results: The MCID was 1.8 (p = 0.04) for the PCS and 1.5 (p = 0.33) for the MCS score. The MIC was 2.7 (p = 0.04) for the PCS and − 1.4 (p = 0.17) for the MCS score. The MDC90 was 8.9 for the PCS and 13.8 for the MCS score. Conclusion: The MCID for the PCS can be used to compare the outcomes between groups, and the MIC can be used to ensure that a clinical difference has been observed for a cohort of patients. The values for the MDC90 can be used to assess whether or not an individual patient has experienced a change.

Publication metadata

Author(s): Clement ND, Weir D, Holland J, Gerrand C, Deehan DJ

Publication type: Article

Publication status: Published

Journal: Knee

Year: 2019

Volume: 26

Issue: 4

Pages: 861-868

Print publication date: 01/08/2019

Online publication date: 17/05/2019

Acceptance date: 30/04/2019

ISSN (print): 0968-0160

ISSN (electronic): 1873-5800

Publisher: Elsevier B.V.


DOI: 10.1016/j.knee.2019.04.018


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