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Addressing safety concerns of probiotic use in preterm babies

Lookup NU author(s): Dr Janet Berrington


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© 2019 Elsevier B.V.More than 10,000 preterm babies worldwide have been enrolled in trials evaluating probiotics administration for the prevention of necrotising enterocolitis, with very few adverse events reported. Despite this, probiotic safety is frequently cited as a concern when using this intervention. This review addresses why a preterm baby may be at risk when administered a live microbial product, short- and longer-term safety data in relation to probiotic use and regulatory aspects around probiotic manufacture and preparations.

Publication metadata

Author(s): Fleming PF, Berrington JE, Jacobs SE

Publication type: Article

Publication status: Published

Journal: Early Human Development

Year: 2019

Volume: 135

Pages: 72-74

Print publication date: 01/08/2019

Online publication date: 30/05/2019

Acceptance date: 02/04/2016

ISSN (print): 0378-3782

ISSN (electronic): 1872-6232

Publisher: Elsevier Ireland Ltd


DOI: 10.1016/j.earlhumdev.2019.05.016


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