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Lookup NU author(s): Professor Sarah O'Brien
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2016 Tam, O'Brien. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Objectives To estimate the annual cost to patients, the health service and society of infectious intestinal disease (IID) from Campylobacter, norovirus and rotavirus. Design Secondary data analysis. Setting The United Kingdom population, 2008â€"9. Main outcome measures Cases and frequency of health services usage due to these three pathogens; associated healthcare costs; direct, out-of-pocket expenses; indirect costs to patients and caregivers. Results The median estimated costs to patients and the health service at 2008â€"9 prices were: Campylobacter £50 million (95% CI: £33mâ€"£75m), norovirus £81 million (95% CI: £63mâ€" £106m), rotavirus £25m (95% CI: £18mâ€"£35m). The costs per case were approximately £30 for norovirus and rotavirus, and £85 for Campylobacter. This was mostly borne by patients and caregivers through lost income or out-of-pocket expenditure. The cost of Campylobacter- related Guillain-Barrà syndrome hospitalisation was £1.26 million (95% CI: £0.4mâ€"£4.2m). Conclusions Norovirus causes greater economic burden than Campylobacter and rotavirus combined. Efforts to control IID must prioritise norovirus. For Campylobacter, estimated costs should be considered in the context of expenditure to control this pathogen in agriculture, food production and retail. Our estimates, prior to routine rotavirus immunisation in the UK, provide a baseline vaccine cost-effectiveness analyses.
Author(s): Tam CC, O'Brien SJ
Publication type: Article
Publication status: Published
Journal: PLoS ONE
Year: 2016
Volume: 11
Issue: 2
Online publication date: 01/02/2016
Acceptance date: 01/09/2015
Date deposited: 22/08/2019
ISSN (electronic): 1932-6203
Publisher: Public Library of Science
URL: https://doi.org/10.1371/journal.pone.0138526
DOI: 10.1371/journal.pone.0138526
PubMed id: 26828435
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