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Lookup NU author(s): Dr Joaquim Majo, Dr Dina Tiniakos
© 2019 Elsevier LtdHistopathological assessment of fibrosis focusing on morphological patterns provides important information for the management of patients with chronic diseases of the kidney, liver and the lung. This review summarizes key histopathological features of pulmonary, renal and hepatic fibrosis and discusses advances in the understanding of the pathogenesis of pulmonary fibrosis and pathogenetic insights with translational implications for renal fibrosis. The review also tackles new staging approaches based on liver fibrosis dynamics and evaluation of fibrosis regression, digital pathology and second harmonic generation microscopy methods for hepatic fibrosis assessment and critical appraisal of non-invasive tests for liver and renal fibrosis evaluation.
Author(s): Majo J, Klinkhammer BM, Boor P, Tiniakos D
Publication type: Review
Publication status: Published
Journal: Current Opinion in Pharmacology
Year: 2019
Volume: 49
Pages: 82-89
Online publication date: 28/10/2019
Acceptance date: 02/04/2019
ISSN (print): 1471-4892
ISSN (electronic): 1471-4973
Publisher: Elsevier Ltd
URL: https://doi.org/10.1016/j.coph.2019.09.009
DOI: 10.1016/j.coph.2019.09.009
