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Acute Macular Neuroretinopathy Associated with Acute Influenza Virus Infection

Lookup NU author(s): Dr Sheila Waugh, Andrew Browning


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© 2019, © 2019 Taylor & Francis Group, LLC.Purpose: To describe a prospective case series of patients with acute macular neuroretinopathy (AMN) associated with acute influenza virus infection Methods: Patients who presented with acute macular neuroretinopathy associated with confirmed influenza virus infection were subject to a detailed clinical history, HLA typing and longitudinal ophthalmological and imaging examinations. Results: Four female patients aged 18 to 32 years were studied. They reported the onset of ocular symptoms between 2 and 5 days after the development of flu like symptoms. Three patients had confirmed acute influenza B infection, while the fourth had influenza A. OCT angiography only demonstrated abnormal choriocapillaris perfusion in 1 patient and early oral Oseltamivir treatment appeared not to affect the ophthalmic outcome in one patient. Conclusion: This is the first report of AMN associated with virologically confirmed acute influenza virus infection. Variation in HLA alleles do not appear to predispose patients to influenza associated AMN.

Publication metadata

Author(s): Ashfaq I, Vrahimi M, Waugh S, Soomro T, Grinton ME, Browning AC

Publication type: Article

Publication status: Published

Journal: Ocular Immunology and Inflammation

Year: 2021

Volume: 29

Issue: 2

Pages: 333-339

Online publication date: 07/11/2019

Acceptance date: 14/10/2019

ISSN (print): 0927-3948

ISSN (electronic): 1744-5078

Publisher: Taylor and Francis Ltd


DOI: 10.1080/09273948.2019.1681470

PubMed id: 31697568


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