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Lookup NU author(s): Dr Sheila Waugh,
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© 2019, © 2019 Taylor & Francis Group, LLC.Purpose: To describe a prospective case series of patients with acute macular neuroretinopathy (AMN) associated with acute influenza virus infection Methods: Patients who presented with acute macular neuroretinopathy associated with confirmed influenza virus infection were subject to a detailed clinical history, HLA typing and longitudinal ophthalmological and imaging examinations. Results: Four female patients aged 18 to 32 years were studied. They reported the onset of ocular symptoms between 2 and 5 days after the development of flu like symptoms. Three patients had confirmed acute influenza B infection, while the fourth had influenza A. OCT angiography only demonstrated abnormal choriocapillaris perfusion in 1 patient and early oral Oseltamivir treatment appeared not to affect the ophthalmic outcome in one patient. Conclusion: This is the first report of AMN associated with virologically confirmed acute influenza virus infection. Variation in HLA alleles do not appear to predispose patients to influenza associated AMN.
Author(s): Ashfaq I, Vrahimi M, Waugh S, Soomro T, Grinton ME, Browning AC
Publication type: Article
Publication status: Published
Journal: Ocular Immunology and Inflammation
Online publication date: 07/11/2019
Acceptance date: 14/10/2019
ISSN (print): 0927-3948
ISSN (electronic): 1744-5078
Publisher: Taylor and Francis Ltd
PubMed id: 31697568
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