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An analysis of the Learning Health System in its First Decade: A Scoping Review

Lookup NU author(s): Dr Matthias WienrothORCiD



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Background Just over a decade has passed since Lynn Etheredge presented a vision for the Learning Health System (LHS) as an opportunity for increasing value of health care via rapid learning from data, and immediate translation to practice and policy. Objectives In the current review, the authors examined themes in literature and rhetoric on the LHS over the past decade in order to understand efforts to realize the LHS in practice, and to identify gaps and opportunities for continuing to move the LHS forward. Methods The authors conducted thematic analysis in 2018 to analyze progress and opportunities over time as compared to the initial “Knowledge Gaps and Uncertainties” initially proposed in 2007. Results The authors found that literature on the LHS has increased over the past decade, with a majority of articles focused on theory and implementation; articles have been increasingly concerned with policy. Conclusions There is a striking need for attention to understanding the ethical and social implications of the LHS, and for exploring opportunities for ensuring that these implications are salient in implementation, practice, and policy efforts.

Publication metadata

Author(s): Platt J, Raj M, Wienroth M

Publication type: Article

Publication status: Published

Journal: Journal of Medical Internet Research

Year: 2020

Volume: 22

Issue: 3

Online publication date: 19/03/2020

Acceptance date: 31/12/2019

Date deposited: 14/01/2020

ISSN (print): 1439-4456

ISSN (electronic): 1438-8871

Publisher: Journal of Medical Internet Research


DOI: 10.2196/17026


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