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Problem solving in clinical practice: The sick infant with low sodium and high potassium

Lookup NU author(s): Dr Yincent TseORCiD, Dr Leigh McDonald, Milan Gopal, Dr HC Johnstone, Professor Timothy Cheetham


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© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.Many paediatricians will be faced with a sick infant who on investigation is found to have hyponatraemia and hyperkalaemia at some time in their career. The focus of initial management includes the treatment of potentially life-threatening hyperkalaemia with concurrent investigation aiming to elucidate whether the underlying cause reflects a primarily renal or endocrine pathology. We describe the presentation of two infants who each presented with one of the more common underlying diagnoses that led to this biochemical disturbance and discuss the approach to immediate treatment, diagnostic work-up and longer term management.

Publication metadata

Author(s): Tse Y, Singhal N, McDonald L, Gopal M, Lall A, Johnstone H, Cheetham T

Publication type: Article

Publication status: Published

Journal: Archives of Disease in Childhood: Education and Practice Edition

Year: 2021

Volume: 106

Pages: 23-27

Print publication date: 21/01/2021

Online publication date: 21/02/2020

Acceptance date: 05/02/2020

ISSN (print): 1743-0585

ISSN (electronic): 1743-0593

Publisher: BMJ Publishing Group


DOI: 10.1136/archdischild-2019-317756

PubMed id: 32086340


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