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Lookup NU author(s): Dr Rachel Botting, Professor Muzlifah Haniffa
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2020 The Authors. Immunology published by John Wiley & Sons Ltd. Establishment of a well-functioning immune network in skin is crucial for its barrier function. This begins in utero alongside the structural differentiation and maturation of skin, and continues to expand and diversify across the human lifespan. The microenvironment of the developing human skin supports immune cell differentiation and has an overall anti-inflammatory profile. Immunologically inert and skewed immune populations found in developing human skin promote wound healing, and as such may play a crucial role in the structural changes occurring during skin development.
Author(s): Botting RA, Haniffa M
Publication type: Review
Publication status: Published
Journal: Immunology
Year: 2020
Volume: 160
Issue: 2
Pages: 149-156
Print publication date: 01/06/2020
Online publication date: 16/03/2020
Acceptance date: 10/03/2020
ISSN (print): 0019-2805
ISSN (electronic): 1365-2567
Publisher: Blackwell Publishing Ltd
URL: https://doi.org/10.1111/imm.13192
DOI: 10.1111/imm.13192
PubMed id: 32173857