Browse by author
Lookup NU author(s): Dr Yu-Tzu WuORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Copyright © Cambridge University Press 2018.Current policy emphasises the importance of 'living well' with dementia, but there has been no comprehensive synthesis of the factors related to quality of life (QoL), subjective well-being or life satisfaction in people with dementia. We examined the available evidence in a systematic review and meta-analysis. We searched electronic databases until 7 January 2016 for observational studies investigating factors associated with QoL, well-being and life satisfaction in people with dementia. Articles had to provide quantitative data and include ?©?75% people with dementia of any type or severity. We included 198 QoL studies taken from 272 articles in the meta-analysis. The analysis focused on 43 factors with sufficient data, relating to 37639 people with dementia. Generally, these factors were significantly associated with QoL, but effect sizes were often small (0.1-0.29) or negligible (<0.09). Factors reflecting relationships, social engagement and functional ability were associated with better QoL. Factors indicative of poorer physical and mental health (including depression and other neuropsychiatric symptoms) and poorer carer well-being were associated with poorer QoL. Longitudinal evidence about predictors of QoL was limited. There was a considerable between-study heterogeneity. The pattern of numerous predominantly small associations with QoL suggests a need to reconsider approaches to understanding and assessing living well with dementia.
Author(s): Martyr A, Nelis SM, Quinn C, Wu Y-T, Lamont RA, Henderson C, Clarke R, Hindle JV, Thom JM, Jones IR, Morris RG, Rusted JM, Victor CR, Clare L
Publication type: Review
Publication status: Published
Journal: Psychological Medicine
Year: 2018
Volume: 48
Issue: 13
Pages: 2130-2139
Print publication date: 01/10/2018
Online publication date: 08/05/2018
Acceptance date: 31/01/2018
ISSN (print): 0033-2917
ISSN (electronic): 1469-8978
Publisher: Cambridge University Press
URL: https://doi.org/10.1017/S0033291718000405
DOI: 10.1017/S0033291718000405
PubMed id: 29734962
