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Land use mix and five-year mortality in later life: Results from the Cognitive Function and Ageing Study

Lookup NU author(s): Dr Yu-Tzu WuORCiD, Professor Matthew Prina, Professor Fiona MatthewsORCiD, Professor Carol Brayne



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


© 2016 The Authors.This study explores the potential modifying effect of age and mediation effect of co-morbidity on the association between land use mix, a measure of neighbourhood walkability, and five-year mortality among the 2424 individuals participating in the year-10 follow-up of the Cognitive Function and Ageing Study in England. Postcodes of participants were mapped onto Lower-layer Super Output Areas, a small area level geographical unit in the UK, and linked to Generalised Land Use data. Cox regression models were fitted to investigate the association. For the younger older age group (75-79 years), the effect of high land use mix on an elevated risk of mortality was mediated by co-morbidity. For older old age groups (80-84, 85+ years), a higher land use mix was directly associated with a 10% lower risk of five-year mortality. The findings suggest differential impacts of land use mix on the health of the younger and older old.

Publication metadata

Author(s): Wu Y-T, Prina AM, Jones A, Barnes LE, Matthews FE, Brayne C, CFAS MRC

Publication type: Article

Publication status: Published

Journal: Health and Place

Year: 2016

Volume: 38

Pages: 54-60

Print publication date: 01/03/2016

Online publication date: 01/02/2016

Acceptance date: 04/12/2015

Date deposited: 21/05/2020

ISSN (print): 1353-8292

ISSN (electronic): 1873-2054

Publisher: Elsevier Ltd


DOI: 10.1016/j.healthplace.2015.12.002

PubMed id: 26798962


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