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Microbe profile: Bacillus subtilis: Model organism for cellular development, and industrial workhorse

Lookup NU author(s): Professor Jeff Errington FRSORCiD, Dr Lizah Van der AartORCiD



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


© 2020 The Authors.Bacillus subtilis is the best studied model organism of the Gram-positive lineage. It is naturally transformable and has an extremely powerful genetic toolbox. It is fast growing and easy to cultivate. It is an important industrial organism, being proficient at secreting proteins and making small fine chemicals, as well as acting as a plant growth promoter. It has been an important model system for studying biofilms. Finally, it makes endospores, which have provided an exceptionally fruitful system for studying various central problems of cellular development, including the generation of asymmetry, cell fate determination and morphogenesis.

Publication metadata

Author(s): Errington J, van der Aa LT

Publication type: Article

Publication status: Published

Journal: Microbiology

Year: 2020

Volume: 166

Issue: 5

Pages: 425-427

Online publication date: 11/05/2020

Acceptance date: 16/04/2020

Date deposited: 17/06/2020

ISSN (print): 1350-0872

ISSN (electronic): 1465-2080

Publisher: Microbiology Society


DOI: 10.1099/mic.0.000922

PubMed id: 32391747


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