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General Movement Assessment Predicts Neuro-Developmental Outcome in Very Low Birth Weight Infants at Two Years – A Five-Year Observational Study

Lookup NU author(s): Dr Vrinda Nair


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© 2020, Dr. K C Chaudhuri Foundation. Objective: To assess the value of general movements (GMs) in predicting the neurodevelopmental outcome using Bayley Scale of Infant Development III (BSID-III) at two years of age in very low birth weight (VLBW) infants. Methods: This is a five-year observational study (January 2012–June 2017). Two hundred twenty-seven VLBW infants were assessed in the neurodevelopmental clinic between Jan 2012 and June 2017. Of these 137 infants had GMs assessments at 3 mo post term (first visit to the clinic). Results: Absence of fidgety movements (FMs) at 3 mo post term had high specificity and negative predictive value for moderate to severe neurodevelopmental outcome in motor, cognition and language domains (composite score less than 70 in the Bayley III scales of Infant development scores). At 3 mo post term, absent FMs had high sensitivity, specificity and negative predictive value (NPV) for cerebral palsy (CP). Conclusions: GMs assessment at 3 mo post term could be considered as an important screening tool for early identification of VLBW infants who are at risk of neurodevelopmental impairment/cerebral palsy.

Publication metadata

Author(s): Barnes F, Graham L, Loganathan P, Nair V

Publication type: Article

Publication status: Published

Journal: Indian Journal of Pediatrics

Year: 2021

Volume: 88

Pages: 28-33

Print publication date: 01/01/2021

Online publication date: 03/06/2020

Acceptance date: 21/05/2020

ISSN (print): 0019-5456

ISSN (electronic): 0973-7693

Publisher: Springer Nature


DOI: 10.1007/s12098-020-03365-1

PubMed id: 32488806


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